Publications

ZORA Publication List

Publications

• 2010

  • Journal Article

    • Yagi, R; Mayer, F; Basler, K (2010). Refined LexA transactivators and their use in combination with the Drosophila Gal4 system. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 107(37):16166-16171.
    • Ahrens, C H; Brunner, E; Basler, K (2010). Quantitative proteomics: a central technology for systems biology. Journal of Proteomics, 73(4):820-827.
    • Schwank, G; Basler, K (2010). Regulation of organ growth by morphogen gradients. Cold Spring Harbor Perspectives in Biology, 2(1):a001669.
    • Song, H; Goetze, S; Bischof, J; Spichiger-Haeusermann, C; Kuster, M; Brunner, E; Basler, K (2010). Coop functions as a corepressor of Pangolin and antagonizes Wingless signaling. Genes and Development, 24(9):881-886.
    • Port, F; Basler, K (2010). Wnt trafficking: new insights into Wnt naturation, secretion and spreading. Traffic, 11(10):1265-1271.
    • Deka, J; Wiedemann, N; Anderle, P; Murphy-Seiler, F; Bultinck, J; Eyckerman, S; Stehle, J C; André, S; Vilain, N; Zilian, O; Robine, S; Delorenzi, M; Basler, K; Aguet, M (2010). Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas. Cancer Research, 70(16):6619-6628.
    • Aegerter-Wilmsen, T; Smith, A C; Christen, A J; Aegerter, C M; Hafen, E; Basler, K (2010). Exploring the effects of mechanical feedback on epithelial topology. Development, 137(3):499-506.

• 2009

  • Journal Article

    • Geuking, P; Narasimamurthy, R; Lemaitre, B; Basler, K; Leulier, F (2009). A non-redundant role for Drosophila Mkk4 and hemipterous/Mkk7 in TAK1-mediated activation of JNK. PLoS ONE, 4(11):e7709.
    • Hamaratoglu, F; Basler, K; Affolter, M (2009). Confronting morphogen gradients: how important are they for growth?. Science Signaling, 2(94):pe67.
    • Song, H; Spichiger-Haeusermann, C; Basler, K (2009). The ISWI-containing NURF complex regulates the output of the canonical Wingless pathway. EMBO Reports, 10(10):1140-1146.
    • Hausmann, G; von Mering, C; Basler, K (2009). The hedgehog signaling pathway: where did it come from?. PLoS Biology, 7(6):e1000146.
    • Mosimann, C; Hausmann, G; Basler, K (2009). Beta-catenin hits chromatin: regulation of Wnt target gene activation. Nature Reviews. Molecular Cell Biology, 10(4):276-286.
    • Narasimamurthy, R; Geuking, P; Ingold, K; Willen, L; Schneider, P; Basler, K (2009). Structure-function analysis of Eiger, the Drosophila TNF homolog. Cell Research, 19(3):392-394.
    • Mosimann, C; Hausmann, G; Basler, K (2009). The role of Parafibromin/Hyrax as a nuclear Gli/Ci-interacting protein in Hedgehog target gene control. Mechanisms of Development, 126(5-6):394-405.
    • Kessler, R; Hausmann, G; Basler, K (2009). The PHD domain is required to link Drosophila Pygopus to Legless/beta-catenin and not to histone H3. Mechanisms of Development, 126(8-9):752-759.
    • Hödl, M; Basler, K (2009). Transcription in the absence of histone H3.3. Current Biology, 19(14):1221-1226.
    • Goetze, S; Qeli, E; Mosimann, C; Staes, A; Gerrits, B; Roschitzki, B; Mohanty, S; Niederer, E M; Laczko, E; Timmerman, E; Lange, V; Hafen, E; Aebersold, R; Vandekerckhove, J; Basler, K; Ahrens, C H; Gevaert, K; Brunner, E (2009). Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster. PLoS Biology, 7(11):e1000236.
    • Grobei, M A; Qeli, E; Brunner, E; Rehrauer, H; Zhang, R; Roschitzki, B; Basler, K; Ahrens, C H; Grossniklaus, U (2009). Deterministic protein inference for shotgun proteomics data provides new insights into Arabidopsis pollen development and function. Genome Research, 19(10):1786-1800.

• 2008

  • Journal Article

    • Schwank, G; Restrepo, S; Basler, K (2008). Growth regulation by Dpp: an essential role for Brinker and a non-essential role for graded signaling levels. Development, 135(24):4003-4013.
    • Affolter, M; Pyrowolakis, G; Weiss, A; Basler, K (2008). Signal-induced repression: the exception or the rule in developmental signaling?. Developmental Cell, 15(1):11-22.
    • Katanaev, V L; Solis, G P; Hausmann, G; Buestorf, S; Katanayeva, N; Schrock, Y; Stuermer, C A O; Basler, K (2008). Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila. The EMBO Journal, 27(3):509-521.
    • Port, F; Kuster, M; Herr, P; Furger, E; Bänziger, C; Hausmann, G; Basler, K (2008). Wingless secretion promotes and requires retromer-dependent cycling of Wntless. Nature Cell Biology, 10(2):178-185.

  • Book Section

    • Bischof, J; Basler, K (2008). Recombinases and their use in gene activation, gene inactivation, and transgenesis. In: Dahmann, C. Drosophila : methods and protocols. Totowa, N.J., US: Springer, 175-195.

• 2007

  • Journal Article

    • Affolter, M; Basler, K (2007). The Decapentaplegic morphogen gradient: from pattern formation to growth regulation.. Nature Reviews. Genetics, 8(9):663-674.
    • Hausmann, G; Bänziger, C; Basler, K (2007). Helping Wingless take flight: how WNT proteins are secreted.. Nature Reviews. Molecular Cell Biology, 8(4):331-336.

• 2006

  • Journal Article

    • Bänziger, C; Soldini, D; Schütt, C; Zipperlen, P; Hausmann, G; Basler, K (2006). Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell, 125(3):509-522.
    • Mosimann, C; Hausmann, G; Basler, K (2006). Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo.. Cell, 125(2):327-341.

• 2005

  • Journal Article

    • Geuking, Peter; Narasimamurthy, Rajesh; Basler, Konrad (2005). A genetic screen targeting the tumor necrosis factor/Eiger signaling pathway: identification of Drosophila TAB2 as a functionally conserved component. Genetics, 171(4):1683-1694.
    • Städeli, R; Basler, K (2005). Dissecting nuclear Wingless signalling: recruitment of the transcriptional co-activator Pygopus by a chain of adaptor proteins.. Mechanisms of Development, 122(11):1171-1182.
    • Hoffmans, R; Städeli, R; Basler, K (2005). Pygopus and legless provide essential transcriptional coactivator functions to armadillo/beta-catenin.. Current Biology, 15(13):1207-1211.
    • Zipperlen, P; Nairz, K; Rimann, I; Basler, K; Hafen, E; Hengartner, M; Hajnal, A (2005). A universal method for automated gene mapping. Genome Biology, 6(2):R19.

• 2004

  • Journal Article

    • Hoffmans, R; Basler, K (2004). Identification and in vivo role of the Armadillo-Legless interaction.. Development, 131(17):4393-4400.
    • Pyrowolakis, G; Hartmann, B; Müller, B; Basler, K; Affolter, M (2004). A simple molecular complex mediates widespread BMP-induced repression during Drosophila development.. Developmental Cell, 7(2):229-240.
    • Scholz, N; Basler, K; Saur, P; Burchardi, H; Felder, S (2004). Outcome prediction in critical care: physicians' prognoses vs. scoring systems.. European Journal of Anaesthesiology : EJA, 21(8):606-611.
    • Moreno, E; Basler, K (2004). dMyc transforms cells into super-competitors.. Cell, 117(1):117-129.
    • Nairz, K; Zipperlen, P; Dearolf, C; Basler, K; Hafen, E (2004). A reverse genetic screen in Drosophila using a deletion-inducing mutagen. Genome Biology, 5(10):R83.

• 2003

  • Journal Article

    • Schweizer, L; Nellen, D; Basler, K (2003). Requirement for Pangolin/dTCF in Drosophila Wingless signaling.. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 100(10):5846-5851.
    • Müller, B; Hartmann, B; Pyrowolakis, G; Affolter, M; Basler, K (2003). Conversion of an extracellular Dpp/BMP morphogen gradient into an inverse transcriptional gradient.. Cell, 113(2):221-233.
    • Végh, M; Basler, K (2003). A genetic screen for hedgehog targets involved in the maintenance of the Drosophila anteroposterior compartment boundary. Genetics, 163(4):1427-1438.

• 2002

  • Journal Article

    • Moreno, E; Basler, K; Morata, G (2002). Cells compete for decapentaplegic survival factor to prevent apoptosis in Drosophila wing development. Nature, 416(6882):755-759.
    • Gerlitz, O; Nellen, D; Ottiger, M; Basler, K (2002). A screen for genes expressed in Drosophila imaginal discs. International Journal of Developmental Biology, 46(1):173-176.
    • Kramps, T; Peter, O; Brunner, E; Nellen, D; Froesch, B; Chatterjee, S; Murone, M; Züllig, S; Basler, K (2002). Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex. Cell, 109(1):47-60.
    • Gerlitz, O; Basler, K (2002). Wingful, an extracellular feedback inhibitor of wingless. Genes and Development, 16(9):1055-1059.
    • Moreno, E; Yan, M; Basler, K (2002). Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily.. Current Biology, 12(14):1263-1268.
    • Ma, Y; Erkner, A; Gong, R; Yao, S; Taipale, J; Basler, K; Beachy, P A (2002). Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched. Cell, 111(1):63-75.
    • Bellotto, M; Bopp, D; Senti, K A; Burke, R; Deak, P; Maroy, P; Dickson, B J; Basler, K; Hafen, E (2002). Maternal-effect loci involved in Drosophila oogenesis and embryogenesis: P element-induced mutations on the third chromosome. International Journal of Developmental Biology, 41(1):149-157.

• 2001

  • Journal Article

    • Hasson, P; Müller, B; Basler, K; Paroush, Z (2001). Brinker requires two corepressors for maximal and versatile repression in Dpp signalling.. The EMBO Journal, 20(20):5725-5736.
    • Chamoun, Z; Mann, R K; Nellen, D; von Kessler, D P; Bellotto, M; Beachy, P A; Basler, K (2001). Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal.. Science, 393(5537):2080-2084.
    • Méthot, N; Basler, K (2001). An absolute requirement for Cubitus interruptus in Hedgehog signaling.. Development, 128(5):733-742.

• 2000

  • Journal Article

    • Sivasankaran, R; Vigano, M Alessandra; Müller, B; Affolter, M; Basler, K (2000). Direct transcriptional control of the Dpp target omb by the DNA binding protein Brinker.. The EMBO Journal, 19(22):6162-6172.

Pagination