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ZORA Publication List
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2024
Journal Article
Oliveira-Paula, Gustavo H; Liu, Sophia; Maira, Alishba; Ressa, Gaia; Ferreira, Graziele C; Quintar, Amado; Jayakumar, Smitha; Almonte, Vanessa; Parikh, Dippal; Valenta, Tomas; Basler, Konrad; Hla, Timothy; Riascos-Bernal, Dario F; Sibinga, Nicholas E S (2024).
The β-catenin C terminus links Wnt and sphingosine-1-phosphate signaling pathways to promote vascular remodeling and atherosclerosis.
Science Advances, 10(11):eadg9278.
2023
Journal Article
Berková, Linda; Fazilaty, Hassan; Yang, Qiutan; Kubovčiak, Jan; Stastna, Monika; Hrckulak, Dusan; Vojtechova, Martina; Dalessi, Tosca; Brügger, Michael David; Hausmann, George; Liberali, Prisca; Korinek, Vladimir; Basler, Konrad; Valenta, Tomas (2023).
Terminal differentiation of villus tip enterocytes is governed by distinct Tgfβ superfamily members.
EMBO Reports, 24(9):e56454.
Gurtner, Alessandra; Borrelli, Costanza; Gonzalez-Perez, Ignacio; Bach, Karsten; Acar, Ilhan E; Núñez, Nicolás G; Crepaz, Daniel; Handler, Kristina; Vu, Vivian P; Lafzi, Atefeh; Stirm, Kristin; Raju, Deeksha; Gschwend, Julia; Basler, Konrad; Schneider, Christoph; Slack, Emma; Valenta, Tomas; Becher, Burkhard; Krebs, Philippe; Moor, Andreas E; Arnold, Isabelle C (2023).
Active eosinophils regulate host defense and immune responses in colitis.
Nature, 615(7950):151-157.
Häfliger, Janine; Schwarzfischer, Marlene; Atrott, Kirstin; Stanzel, Claudia; Morsy, Yasser; Wawrzyniak, Marcin; Lang, Silvia; Valenta, Tomas; Basler, Konrad; Rogler, Gerhard; Scharl, Michael; Spalinger, Marianne R (2023).
Glycoprotein (GP)96 is essential for maintaining intestinal epithelial architecture by supporting its self-renewal capacity.
Cellular and Molecular Gastroenterology and Hepatology, 15(3):717-739.
2022
2021
Journal Article
Degirmenci, Bahar; Dincer, Cansu; Demirel, Habibe Cansu; Berkova, Linda; Moor, Andreas E; Kahraman, Abdullah; Hausmann, George; Aguet, Michel; Tuncbag, Nurcan; Valenta, Tomas; Basler, Konrad (2021).
Epithelial Wnt secretion drives the progression of inflammation-induced colon carcinoma in murine model.
iScience, 24(12):103369.
Borrelli, Costanza; Valenta, Tomas; Handler, Kristina; Vélez, Karelia; Gurtner, Alessandra; Moro, Giulia; Lafzi, Atefeh; De Vargas Roditi, Laura; Hausmann, George; Arnold, Isabelle C; Moor, Andreas E; Basler, Konrad (2021).
Differential regulation of β-catenin-mediated transcription via N- and C-terminal co-factors governs identity of murine intestinal epithelial stem cells.
Nature Communications, 12:1368.
Diener, Johanna; Baggiolini, Arianna; Pernebrink, Mattias; Dalcher, Damian; Lerra, Luigi; Cheng, Phil F; Varum, Sandra; Häusel, Jessica; Stierli, Salome; Treier, Mathias; Studer, Lorenz; Basler, Konrad; Levesque, Mitchell P; Dummer, Reinhard; Santoro, Raffaella; Cantù, Claudio; Sommer, Lukas (2021).
Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4.
Nature Communications, 12(1):5056.
Fazilaty, Hassan; Brügger, Michael David; Valenta, Tomas; Szczerba, Barbara M; Berkova, Linda; Doumpas, Nikolaos; Hausmann, George; Scharl, Michael; Basler, Konrad (2021).
Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage.
Cell Reports, 36(5):109484.
2020
Journal Article
Saxena, Meera; Kalathur, Ravi KR; Rubinstein, Natalia; Vettiger, Andrea; Sugiyama, Nami; Neutzner, Melanie; Coto-Llerena, Mairene; Kancherla, Venkatesh; Ercan, Caner; Piscuoglio, Salvatore; Fischer, Jonas; Fagiani, Ernesta; Cantù, Claudio; Basler, Konrad; Christofori, Gerhard (2020).
A Pygopus 2-histone interaction is critical for cancer cell de-differentiation and progression in malignant breast cancer.
Cancer Research, 80(17):3631-3648.
Working Paper
Borrelli, Costanza; Valenta, Tomas; Handler, Kristina; Vélez, Karelia; Moro, Giulia; Lafzi, Atefeh; de Vargas Roditi, Laura; Hausmann, George; Moor, Andreas E; Basler, Konrad (2020).
Discrete regulation of β-catenin-mediated transcription governs identity of intestinal epithelial stem cells.
bioRxiv 103499, Cold Spring Harbor Laboratory.
Zimmerli, Dario; Borrelli, Costanza; Jauregi-Miguel, Amaia; Söderholm, Simon; Brütsch, Salome; Doumpas, Nikolaos; Reichmuth, Jan; Murphy-Seiler, Fabienne; Aguet, Michel; Basler, Konrad; Moor, Andreas E; Cantù, Claudio (2020).
TBX3 acts as tissue-specific component of the Wnt/β-catenin enhanceosome.
bioRxiv 053561, Cold Spring Harbor Laboratory.
2019
Journal Article
Kabakci, Zeynep; Käppeli, Simon; Cantù, Claudio; Jensen, Lasse D; König, Christiane; Toggweiler, Janine; Gentili, Christian; Ribaudo, Giovanni; Zagotto, Giuseppe; Basler, Konrad; Pinna, Lorenzo A; Cozza, Giorgio; Ferrari, Stefano (2019).
Pharmacophore-guided discovery of CDC25 inhibitors causing cell cycle arrest and tumor regression.
Scientific Reports, 9(1):1335.
Brunner, Erich; Yagi, Ryohei; Debrunner, Marc; Beck-Schneider, Dezirae; Burger, Alexa; Escher, Eliane; Mosimann, Christian; Hausmann, George; Basler, Konrad (2019).
CRISPR-induced double-strand breaks trigger recombination between homologous chromosome arms.
Life Science Alliance, 2(3):e201800267.
Zurkirchen, Luis; Varum, Sandra; Giger, Sonja; Klug, Annika; Häusel, Jessica; Bossart, Raphaël; Zemke, Martina; Cantù, Claudio; Atak, Zeynep Kalender; Zamboni, Nicola; Basler, Konrad; Sommer, Lukas (2019).
Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner.
Nature Communications, 10:2192.
Varum, Sandra; Baggiolini, Arianna; Zurkirchen, Luis; Atak, Zeynep Kalender; Cantù, Claudio; Marzorati, Elisa; Bossart, Raphaël; Wouters, Jasper; Häusel, Jessica; Tuncer, Eylül; Zingg, Daniel; Veen, Dominiek; John, Nessy; Balz, Marcel; Levesque, Mitchell P; Basler, Konrad; Aerts, Stein; Zamboni, Nicola; Dummer, Reinhard; Sommer, Lukas (2019).
Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation.
Cell Stem Cell, 24(4):637-653.e9.
Shokri, Leila; Inukai, Sachi; Hafner, Antonina; Weinand, Kathryn; Hens, Korneel; Vedenko, Anastasia; Gisselbrecht, Stephen S; Dainese, Riccardo; Bischof, Johannes; Furger, Edy; Feuz, Jean-Daniel; Basler, Konrad; Deplancke, Bart; Bulyk, Martha L (2019).
A Comprehensive Drosophila melanogaster Transcription Factor Interactome.
Cell Reports, 27(3):955-970.e7.
2018
Journal Article
Cantù, Claudio; Felker, Anastasia; Zimmerli, Dario; Prummel, Karin D; Cabello, Elena M; Chiavacci, Elena; Méndez-Acevedo, Kevin M; Kirchgeorg, Lucia; Burger, Sibylle; Ripoll, Jorge; Valenta, Tomas; Hausmann, George; Vilain, Nathalie; Aguet, Michel; Burger, Alexa; Panáková, Daniela; Basler, Konrad; Mosimann, Christian (2018).
Mutations in and genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling.
Genes and Development, 32(21-22):1443-1458.
Bischof, Johannes; Duffraisse, Marilyne; Furger, Edy; Ajuria, Leiore; Giraud, Guillaume; Vanderperre, Solene; Paul, Rachel; Björklund, Mikael; Ahr, Damien; Ahmed, Alexis W; Spinelli, Lionel; Brun, Christine; Basler, Konrad; Merabet, Samir (2018).
Generation of a versatile BiFC ORFeome library for analyzing protein-protein interactions in live.
eLife, 7:e38853.
Zingg, Daniel; Debbache, Julien; Peña-Hernández, Rodrigo; Antunes, Ana T; Schaefer, Simon M; Cheng, Phil F; Zimmerli, Dario; Haeusel, Jessica; Calçada, Raquel R; Tuncer, Eylul; Zhang, Yudong; Bossart, Raphaël; Wong, Kwok-Kin; Basler, Konrad; Dummer, Reinhard; Santoro, Raffaella; Levesque, Mitchell P; Sommer, Lukas (2018).
EZH2-mediated primary cilium deconstruction drives metastatic melanoma formation.
Cancer Cell, 34(1):69-84.
Spletter, Maria L; Barz, Christiane; Yeroslaviz, Assa; Zhang, Xu; Lemke, Sandra B; Bonnard, Adrien; Brunner, Erich; Cardone, Giovanni; Basler, Konrad; Habermann, Bianca H; Schnorrer, Frank (2018).
A transcriptomics resource reveals a transcriptional transition during ordered sarcomere morphogenesis in flight muscle.
eLife, 7:e34058.
Zimmerli, Dario; Cecconi, Virginia; Valenta, Tomas; Hausmann, George; Cantù, Claudio; Restivo, Gaetana; Hafner, Jürg; Basler, Konrad; van den Broek, Maries (2018).
WNT ligands control initiation and progression of human papillomavirus-driven squamous cell carcinoma.
Oncogene, 37(27):3753-3762.
2017
Journal Article
Marty, Florian; Rago, Gianluca; Smith, Donald F; Gao, Xiaoli; Eijkel, Gert B; MacAleese, Luke; Bonn, Mischa; Brunner, Erich; Basler, Konrad; Heeren, Ron M A (2017).
Combining ToF-SIMS imaging mass spectrometry and CARS microspectroscopy reveals lipid patterns reminiscent of gene expression patterns in the wing imaginal disc of Drosophila melanogaster.
Analytical Chemistry, 89(18):9664-9670.
Blyszczuk, Przemyslaw; Müller-Edenborn, Björn; Valenta, Tomas; Osto, Elena; Stellato, Mara; Behnke, Silvia; Glatz, Katharina; Basler, Konrad; Lüscher, Thomas F; Distler, Oliver; Eriksson, Urs; Kania, Gabriela (2017).
Transforming growth factor-β-dependent Wnt secretion controls myofibroblast formation and myocardial fibrosis progression in experimental autoimmune myocarditis.
European Heart Journal, 38(18):1413-1425.
Cantù, Claudio; Pagella, Pierfrancesco; Shajiei, Tania D; Zimmerli, Dario; Valenta, Tomas; Hausmann, George; Basler, Konrad; Mitsiadis, Thimios A (2017).
A cytoplasmic role of Wnt/β-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation.
Science Signaling, 10(465):eaah4598.
2016
Journal Article
Valenta, Tomas; Degirmenci, Bahar; Moor, Andreas E; Herr, Patrick; Zimmerli, Dario; Moor, Matthias B; Hausmann, George; Cantù, Claudio; Aguet, Michel; Basler, Konrad (2016).
Wnt ligands secreted by subepithelial mesenchymal cells are essential for the survival of intestinal stem cells and gut homeostasis.
Cell Reports, 15:1-8.
Pagination
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