Publications

ZORA Publication List

Publications

• 2023

  • Journal Article

    • Jetzer, Tania; Studer, Luka; Bieri, Manuela; Greber, Urs; Hemmi, Silvio (2023). Engineered human adenoviruses of species B and C report early, intermediate early and late viral gene expression. Human Gene Therapy, 34(23-24):1230-1247.

• 2022

  • Journal Article

    • Kannan, Abhilash; Suomalainen, Maarit; Volle, Romain; Bauer, Michael; Amsler, Marco; Trinh, Hung V; Vavassori, Stefano; Pachlopnik Schmid, Jana; Vilhena, Guilherme; Marin-Gonzalez, Alberto; Pérez, Rubén; Franceschini, Andrea; von Mering, Christian; Hemmi, Silvio; Greber, Urs F (2022). Sequence-Specific Features of Short Double-Strand, Blunt-End RNAs Have RIG-I- and Type 1 Interferon-Dependent or -Independent Anti-Viral Effects. Viruses, 14(7):1407.

• 2021

  • Journal Article

    • Bauer, Michael; Gomez-Gonzalez, Alfonso; Suomalainen, Maarit; Schilling, Nicolas; Hemmi, Silvio; Greber, Urs F (2021). A viral ubiquitination switch attenuates innate immunity and triggers nuclear import of virion DNA and infection. Science Advances, 7(51):eabl7150.
    • Bieri, Manuela; Hendrickx, Rodinde; Bauer, Michael; Yu, Bin; Jetzer, Tania; Dreier, Birgit; Mittl, Peer R E; Sobek, Jens; Plückthun, Andreas; Greber, Urs F; Hemmi, Silvio (2021). The RGD-binding integrins αvβ6 and αvβ8 are receptors for mouse adenovirus-1 and -3 infection. PLoS Pathogens, 17(12):e1010083.

• 2020

  • Journal Article

    • Georgi, Fanny; Andriasyan, Vardan; Witte, Robert; Murer, Luca; Hemmi, Silvio; Yu, Lisa; Grove, Melanie; Meili, Nicole; Kuttler, Fabien; Yakimovich, Artur; Turcatti, Gerardo; Greber, Urs F (2020). The FDA-approved drug Nelfinavir inhibits lytic cell-free, but not cell-associated non-lytic transmission of human adenovirus. Antimicrobial Agents and Chemotherapy, 64(9):e01002-20.
    • Prasad, Vibhu; Suomalainen, Maarit; Jasiqi, Yllza; Hemmi, Silvio; Hearing, Patrick; Hosie, Louise; Burgert, Hans-Gerhard; Greber, Urs F (2020). The UPR sensor IRE1α and the adenovirus E3-19K glycoprotein sustain persistent and lytic infections. Nature Communications, 11:1997.

• 2019

  • Journal Article

    • Bauer, Michael; Flatt, Justin W; Seiler, Daria; Cardel, Bettina; Emmenlauer, Mario; Boucke, Karin; Suomalainen, Maarit; Hemmi, Silvio; Greber, Urs F (2019). The E3 Ubiquitin Ligase Mind Bomb 1 Controls Adenovirus Genome Release at the Nuclear Pore Complex. Cell Reports, 29(12):3785-3795.e8.

• 2018

  • Journal Article

    • Stichling, Nicole; Suomalainen, Maarit; Flatt, Justin W; Schmid, Markus; Pacesa, Martin; Hemmi, Silvio; Jungraithmayr, Wolfgang; Maler, Mareike D; Freudenberg, Marina A; Plückthun, Andreas; May, Tobias; Köster, Mario; Fejer, György; Greber, Urs F (2018). Lung macrophage scavenger receptor SR-A6 (MARCO) is an adenovirus type-specific virus entry receptor. PLoS Pathogens, 14(3):e1006914.

• 2017

  • Journal Article

    • Item, Flurin; Wueest, Stephan; Lemos, Vera; Stein, Sokrates; Lucchini, Fabrizio C; Denzler, Rémy; Fisser, Muriel C; Challa, Tenagne D; Pirinen, Eija; Kim, Youngsoo; Hemmi, Silvio; Gulbins, Erich; Gross, Atan; O'Reilly, Lorraine A; Stoffel, Markus; Auwerx, Johan; Konrad, Daniel (2017). Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function. Nature Communications, 8:480.
    • Pacesa, Martin; Hendrickx, Rodinde; Bieri, Manuela; Flatt, Justin W; Greber, Urs F; Hemmi, Silvio (2017). Small-size recombinant adenoviral hexon protein fragments for the production of virus-type specific antibodies. Virology Journal, 14(1):158-171.
    • Prasad, Vibhu; Suomalainen, Maarit; Hemmi, Silvio; Greber, Urs F (2017). Cell Cycle-Dependent Kinase Cdk9 Is a Postexposure Drug Target against Human Adenoviruses. ACS Infectious Diseases, 3(6):398-405.

• 2016

  • Journal Article

    • Luisoni, Stefania; Bauer, Michael; Prasad, Vibhu; Boucke, Karin; Papadopoulos, Chrisovalantis; Meyer, Hemmo; Hemmi, Silvio; Suomalainen, Maarit; Greber, Urs F (2016). Endosomophagy clears disrupted early endosomes but not virus particles during virus entry into cells. Matters:online.
    • Cho, Young-Suk; Do, Manh-Hung; Kwon, Se-Young; Moon, Changjong; Kim, Kwonseop; Lee, Keesook; Lee, Sang-Jin; Hemmi, Silvio; Joo, Young-Eun; Kim, Min Soo; Jung, Chaeyong (2016). Efficacy of CD46-targeting chimeric Ad5/35 adenoviral gene therapy for colorectal cancers. OncoTarget, 7(25):38210-38223.
    • Zafar, Sadia; Parviainen, Suvi; Siurala, Mikko; Hemminki, Otto; Havunen, Riikka; Tähtinen, Siri; Bramante, Simona; Vassilev, Lotta; Wang, Hongjie; Lieber, Andre; Hemmi, Silvio; de Gruijl, Tanja; Kanerva, Anna; Hemminki, Akseli (2016). Intravenously usable fully serotype 3 oncolytic adenovirus coding for CD40L as an enabler of dendritic cell therapy. OncoImmunology, 6(2):e1265717.
    • Raddi, Najat; Vigant, Frédéric; Wagner-Ballon, Oriane; Giraudier, Stéphane; Custers, Jerome; Hemmi, Silvio; Benihoud, Karim (2016). Pseudotyping serotype 5 adenovirus with the fiber from other serotypes uncovers a key role of the fiber protein in adenovirus 5-induced thrombocytopenia. Human Gene Therapy, 27(2):193-201.

• 2015

  • Journal Article

    • Cheng, Phil F; Shakhova, Olga; Widmer, Daniel S; Eichhoff, Ossia M; Zingg, Daniel; Frommel, Sandra C; Belloni, Benedetta; Raaijmakers, Marieke I G; Goldinger, Simone M; Santoro, Raffaella; Hemmi, Silvio; Sommer, Lukas; Dummer, Reinhard; Levesque, Mitchell P (2015). Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma. Genome Biology, 16:42.

• 2014

  • Journal Article

    • Prasad, Vibhu; Suomalainen, Maarit; Pennauer, Mirjam; Yakimovich, Artur; Andriasyan, Vardan; Hemmi, Silvio; Greber, Urs F (2014). Chemical induction of unfolded protein response enhances cancer cell killing through lytic virus infection. Journal of Virology, 88(22):13086-13098.

• 2013

  • Journal Article

    • Trinh, Hung V; Grossmann, Jonas; Gehrig, Peter; Roschitzki, Bernd; Schlapbach, Ralph; Greber, Urs F; Hemmi, Silvio (2013). iTRAQ-based and label-free proteomics approaches for studies of human adenovirus infections. International Journal of Proteomics, 2013:581862.
    • Widmer, Daniel S; Hoek, Keith S; Cheng, Phil F; Eichhoff, Ossia M; Biedermann, Thomas; Raaijmakers, Marieke I G; Hemmi, Silvio; Dummer, Reinhard; Levesque, Mitchell P (2013). Hypoxia contributes to melanoma heterogeneity by triggering HIF1α-dependent phenotype switching. Journal of Investigative Dermatology, 133(10):2436-2443.

• 2012

  • Journal Article

    • Trinh, H V; Lesage, G; Chennamparampil, V; Vollenweider, B; Burckhardt, C J; Schauer, S; Havenga, M; Greber, U F; Hemmi, S (2012). Avidity binding of human adenovirus serotypes 3 and 7 to the membrane cofactor CD46 triggers infection. Journal of Virology, 86(3):1623-1637.

• 2011

  • Journal Article

    • Burckhardt, C J; Suomalainen, M; Schoenenberger, P; Boucke, K; Hemmi, S; Greber, U F (2011). Drifting Motions of the Adenovirus Receptor CAR and Immobile Integrins Initiate Virus Uncoating and Membrane Lytic Protein Exposure. Cell Host & Microbe, 10(2):105-117.
    • Lütschg, V; Boucke, K; Hemmi, S; Greber, U F (2011). Chemotactic antiviral cytokines promote infectious apical entry of human adenovirus into polarized epithelial cells. Nature Communications, 2:391.
    • Hemmi, S; Vidovszky, M Z; Ruminska, J; Ramelli, S; Decurtins, W; Greber, U F; Harrach, B (2011). Genomic and phylogenetic analyses of murine adenovirus 2. Virus Research, 160(1-2):128-135.
    • Buschmann, J; Welti, M; Hemmi, S; Neuenschwander, P; Baltes, C; Giovanoli, P; Rudin, M; Calcagni, M (2011). 3D co-cultures of osteoblasts and endothelial cells in DegraPol foam: Histological and high field MRI analyses of pre-engineered capillary networks in bone grafts. Tissue engineering. Part C, 17(3-4):291-299.

• 2010

  • Journal Article

    • Hemminki, O; Bauerschmitz, G; Hemmi, S; Lavilla-Alonso, S; Diaconu, I; Guse, K; Koski, A; Desmond, R A; Lappalainen, M; Kanerva, A; Cerullo, V; Pesonen, S; Hemminki, A (2010). Oncolytic adenovirus based on serotype 3. Cancer Gene Therapy, 18:288-296.
    • Kälin, S; Amstutz, B; Gastaldelli, M; Wolfrum, N; Boucke, K; Havenga, M; Digennaro, F; Liska, N; Hemmi, S; Greber, U F (2010). Macropinocytotic uptake and infection of human epithelial cells with species B2 adenovirus type 35. Journal of Virology, 84(10):5336-5350.
    • Fontecedro, A C; Lutschg, V; Eichhoff, O; Dummer, R; Greber, U F; Hemmi, S (2010). Analysis of adenovirus trans-complementation-mediated gene expression controlled by melanoma-specific TETP promoter in vitro. Virology Journal, 7(1):175.

• 2009

  • Journal Article

    • Schlegel, N C; Eichhoff, O M; Hemmi, S; Werner, S; Dummer, R; Hoek, K S (2009). Id2 suppression of p15 counters TGF-beta-mediated growth inhibition of melanoma cells.counters TGF-beta-mediated growth inhibition of melanoma cells. Pigment Cell & Melanoma Research, 22(4):445-453.

• 2008

  • Journal Article

    • Amstutz, B; Gastaldelli, M; Kälin, S; Imelli, N; Boucke, K; Wandeler, E; Mercer, J; Hemmi, S; Greber, U F (2008). Subversion of CtBP1-controlled macropinocytosis by human adenovirus serotype 3. The EMBO Journal, 27(7):956-969.
    • Hoek, K S; Eichhoff, O M; Schlegel, N C; Döbbeling, U; Kobert, N; Schaerer, L; Hemmi, S; Dummer, R (2008). In vivo switching of human melanoma cells between proliferative and invasive states. Cancer Research, 68(3):650-656.

• 2007

  • Journal Article

    • Fleischli, C; Sirena, D; Lesage, G; Havenga, M J E; Cattaneo, R; Greber, U F; Hemmi, S (2007). Species B adenovirus serotypes 3, 7, 11 and 35 share similar binding sites on the membrane cofactor protein CD46 receptor.. Journal of General Virology, 88(11):2925-2934.

• 2006

  • Journal Article

    • Schmitz, M; Graf, C; Gut, T; Sirena, D; Peter, I; Dummer, R; Greber, U F; Hemmi, S (2006). Melanoma cultures show different susceptibility towards E1A-, E1B-19 kDa- and fiber-modified replication-competent adenoviruses.. Gene Therapy, 13(11):893-905.

• 2005

  • Journal Article

    • Sirena, D; Ruzsics, Z; Schaffner, Walter; Greber, U F; Hemmi, S (2005). The nucleotide sequence and a first generation gene transfer vector of species B human adenovirus serotype 3.. Virology, 343(2):283-298.
    • Fleischli, C; Verhaagh, S; Havenga, M; Sirena, D; Schaffner, Walter; Cattaneo, R; Greber, U F; Hemmi, S (2005). The distal short consensus repeats 1 and 2 of the membrane cofactor protein CD46 and their distance from the cell membrane determine productive entry of species B adenovirus serotype 35.. Journal of Virology, 79(15):10013-10022.
    • Meier, O; Gastaldelli, M; Boucke, K; Hemmi, S; Greber, U F (2005). Early steps of clathrin-mediated endocytosis involved in phagosomal escape of Fcgamma receptor-targeted adenovirus.. Journal of Virology, 79(4):2604-2613.

• 2004

  • Journal Article

    • Sirena, D; Lilienfeld, B; Eisenhut, M; Kälin, S; Boucke, K; Beerli, R R; Vogt, Lorenz; Ruedl, C; Bachmann, M F; Greber, U F; Hemmi, S (2004). The human membrane cofactor CD46 is a receptor for species B adenovirus serotype 3.. Journal of Virology, 78(9):4454-4462.
    • Imelli, N; Meier, O; Boucke, K; Hemmi, S; Greber, U F (2004). Cholesterol is required for endocytosis and endosomal escape of adenovirus type 2.. Journal of Virology, 78(6):3089-3098.

• 2003

  • Journal Article

    • Nagel, H; Maag, S; Tassis, A; Nestlé, F O; Greber, U F; Hemmi, S (2003). The alphavbeta5 integrin of hematopoietic and nonhematopoietic cells is a transduction receptor of RGD-4C fiber-modified adenoviruses.. Gene Therapy, 10(19):1643-1653.
    • Peter, I; Graf, C; Dummer, R; Schaffner, W; Greber, U F; Hemmi, S (2003). A novel attenuated replication-competent adenovirus for melanoma therapy.. Gene Therapy, 10(7):530-9.

• 2002

  • Journal Article

    • Meier, O; Boucke, K; Hammer, S V; Keller, S; Stidwill, R P; Hemmi, S; Greber, U F (2002). Adenovirus triggers macropinocytosis and endosomal leakage together with its clathrin-mediated uptake.. Journal of Cell Biology, 158(6):1119-1131.

• 2001

  • Journal Article

    • Ebbinghaus, C; Al-Jaibaji, A; Operschall, E; Schöffel, A; Peter, I; Greber, U F; Hemmi, S (2001). Functional and selective targeting of adenovirus to high-affinity Fcgamma receptor I-positive cells by using a bispecific hybrid adapter.. Journal of Virology, 75(1):480-489.